Key clinical point : Data do not support an association between vaccination and increased risk of MS.
Major finding : The odds of MS were lower in participants who received vaccination, compared with participants without autoimmune disease (odds ratio, 0.870).
Study details : A systematic retrospective analysis of claims data for 12,262 patients with MS and 210,773 controls.
Disclosures: A grant from the German Federal Ministry of Education and Research Competence Network MS supported the study. The authors had no relevant conflicts.
Citation: Hapfelmeier A et al. Neurology. 2019 Jul 30. doi: 10.1212/WNL.0000000000008012 .