Parkinson's Disease
From the Journals
APOE genotype directly regulates alpha-synuclein accumulation
Two studies synergistically show how the APOE4 genotype is associated with cognitive decline in patients with Lewy body dementia.
Conference Coverage
Pimavanserin reduced dementia-related psychotic symptoms without affecting cognition
SAN DIEGO – The adverse event profile of the second-generation antipsychotic appears more benign than that typically seen with antipsychotics in...
From the Journals
Parkinson’s patients can lose swimming ability after deep brain stimulation
Ability returned within 30 minutes of turning off the stimulator, and loss of ability recurred within 30 minutes of resuming stimulation.
Literature Review
Antibiotic use may increase the risk of Parkinson’s disease
Use of antianaerobic or tetracycline antimicrobials may be associated with the later development of Parkinson’s disease.
Conference Coverage
Baseline subtypes predict dementia and death in patients with Parkinson’s disease
ST. LOUIS – Clinicians should assess cognitive and psychiatric symptoms at baseline.
Literature Review
Increased Parkinson’s disease risk seen with bipolar disorder
People with bipolar disorder may be at increased risk of developing Parkinson’s disease in later life.
News from the FDA/CDC
FDA approves istradefylline for Parkinson’s disease
Conference Coverage
Imaging predicts early postural instability in Parkinson’s disease
PHILADELPHIA – Using imaging and clinical data, researchers developed a seven-item scale to identify patients with...
From the Journals
Anticholinergic drugs linked to dementia in older populations
“Associations were stronger in [dementia] cases diagnosed before the age of 80 years,” the researchers noted.
Literature Review
CSF neurofilament light level could aid in diagnosis
The level of neurofilament light in CSF may distinguish frontotemporal dementia from other dementias and Parkinson’s disease from atypical...
Literature Review
Treatment for hepatitis C reduces risk of Parkinson’s disease
Data support the hypothesis that hepatitis C virus infection is a risk factor for incident Parkinson’s disease.