Women with a reproductive period of 21-30 years were 33% more likely to develop dementia than were those with a longer period (HR, 1.33)
“Reproductive events that signal different exposures to estrogen, like pregnancy and reproductive period may play a role in modulating dementia risk,” Dr. Gilsanz said. “Women who are less likely to have a miscarriage may have different hormonal milieu that may be neuroprotective. Underlying health conditions increasing the risk of miscarriages may also elevate risk of dementia.”
She had no financial disclosures.
SOURCE: Gilsanz P et al. AAIC 2018, Abstract P3-587