Clinical Review

Managing preterm birth to lower the risk of cerebral palsy

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For these reasons and because sub-acute intrauterine inflammation may harm the fetus, delivery can be considered after 32 completed weeks of gestation if fetal lung maturity is confirmed. A meta-analysis of four randomized controlled trials that compared intentional delivery with expectant management after pPROM between 30 and 36 weeks of gestation found no difference in neonatal outcomes.32

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