Child Psychiatry Consult

ADHD in the long term


 

What does ADHD predict for adults?

It appears that overall, adults who were diagnosed with ADHD as children show poorer functional outcomes than did those who weren’t, and there is a step-wise relationship when considering adults whose symptoms persist, with more severe outcomes compared with adults whose symptoms have desisted, who in turn have worse outcomes than adults who were never diagnosed with ADHD. Educational attainments follow this pattern with the highest average levels of education in the non-ADHD group and the lowest average years in the group with persistent symptoms. Occupational success and percent receiving public assistance again separated between each group, with the symptom persisters faring the worst, the symptom desisters better, and those never affected by ADHD, the best. In terms of emotional disorders, it was only the symptom persisters who suffered from higher rates of mood and anxiety disorders. Similarly, only the symptom persisters had significantly more marijuana use disorders. No other substance use disorders or legal outcomes were significant.

How does this affect how we approach treatment?

Clinicians and researchers who specialize in ADHD have been arguing for ADHD to be treated as more of a chronic disease and for impairment to be the focus of treatment, rather than simply symptom control.10 With what we know about long-term functional impairment, there is reason to consider a more holistic picture of a child or an adolescent and how they are functioning in their academic, emotional, and social domains. A meta-analysis of treatment and long-term outcomes suggests that psychostimulant treatment, psychotherapy treatment, and combined treatment all improve long-term functioning, especially self-esteem, social functioning, and academic functioning, with combined psychotherapeutic and pharmacologic treatments associated with the highest effect sizes.11

Dr. Sarah Guth is an assistant professor in the department of psychiatry at the University of Vermont Medical Center and the University of Vermont, both in Burlington.

Dr. Sarah Guth

For those who treat ADHD, it is our job to provide education to families about the chronic risks associated with the diagnosis, and the importance of offering multimodal therapy that can address family factors that might be contributing to risks, as well as the child’s overall well-being. If we are to make sense of how adults may experience impairment even in the absence of ongoing symptoms, we might look at how their overall wellness was interrupted during development. Maybe they fell into a different crowd of kids? Maybe they stopped achieving at school in a way that changed the achievement trajectory they were on? Maybe they impulsively picked up substances or got in trouble with the law? These events can have lasting impacts on well-being. We must use medicine and psychotherapy to help with symptoms, but we must look beyond treating illness and use evidence-based strategies to promote wellness at the level of the entire family.

Dr. Guth is an assistant professor in the department of psychiatry at the University of Vermont Medical Center and the University of Vermont, both in Burlington. She works with children and adolescents as well as women in the perinatal period. She has no relevant financial disclosures.

References

1. Psychol Med. 2006 Feb;36(2):159-65.

2. J Am Acad Child Adolesc Psychiatry. 2016 Nov;55(11):937-44.e4.

3. J Am Acad Child Adolesc Psychiatry. 2018 Aug;57(8):571-82.e1.

4. J Am Acad Child Adolesc Psychiatry. 2017 Aug;56(8):687-95.e7.

5. J Am Acad Child Adolesc Psychiatry. 2016 Nov;55(11):945-52.e2.

6. J Am Acad Child Adolesc Psychiatry. 2009 May;48(5):484-500.

7. J Atten Disord. 2017 Sep 1:1087054717730610. doi: 10.1177/1087054717730610.

8. J Atten Disord. 2016 May;20(5):383-9.

9. Eur Child Adolesc Psychiatry. 2014 Feb;23(2):95-102.

10. JAMA Pediatr. 2018 Aug 13. doi: 10.1001/jamapediatrics.2018.1642.

11. PLoS One. 2015 Feb 25;10(2):e0116407.

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