The Randomized Intervention for Children with Vesicoureteral Reflux (RIVUR) study seeks to enroll infants and children between the ages of 2 months and 6 years who have had a first or second VUR infection within 112 days of study enrollment. Participants receive a daily dose of an antibiotic or a placebo for up to 2 years. For more information, go to www.clinicaltrials.gov/ct2/show/NCT00405704?term=RIVUR&rank=1