Musculoskeletal Disorders
From the Journals
Greater reductions in knee OA pain seen with supportive rather than flexible shoes
Compared with patients who wore flat flexible shoes, those who wore stable supportive shoes had greater improvement after 6 months.
From the Journals
Data call for biologics trials in undertreated juvenile arthritis subtype
Many children with enthesitis-related arthritis have significant disease burden despite treatment with biologics currently approved for adults...
Conference Coverage
JIA guideline calls for earlier use of targeted therapies
Patients with juvenile idiopathic arthritis can benefit from earlier introduction of biologic DMARDs, an expert consensus panel said.
Conference Coverage
Gene-replacement therapy shows promise in X-linked myotubular myopathy
An investigational gene therapy decreases ventilator dependence and may improve motor development in children with a rare, life-threatening...
From the Journals
JIA arthritis and uveitis flares ‘often run parallel’
Worsening arthritis in children with juvenile idiopathic arthritis could be a sign for needing a prompt eye examination.
Conference Coverage
Acute flaccid myelitis: More likely missed than diagnosed
A retrospective series reports that 78% of children with acute flaccid myelitis are misdiagnosed initially, causing delays in treatment.
Conference Coverage
Nusinersen provides continued benefits to presymptomatic children with SMA
Most children developed normally in an interim analysis of the NURTURE trial that did not find any new safety concerns.
From the Journals
New lupus classification criteria perform well in children, young adults
A new study upholds the accuracy of the 2019 ACR-EULAR classification criteria in patients aged 21 years and younger.
News from the FDA/CDC
Golimumab approval extended to polyarticular-course JIA and juvenile PsA
The expanded approval to include pediatric indications came as part of a review of a clinical trial mandated by the Pediatric Research Equity Act...
From the Journals
Orthopedic problems in children can be the first indication of acute lymphoblastic leukemia
News from the FDA/CDC
FDA adds polyarticular-course JIA to approved indications for tofacitinib
The approval is the fourth indication in the United States for tofacitinib after approvals for treatment of adults with rheumatoid arthritis,...