Spondyloarthropathies
Feature
Novel study explores link between primary immunodeficiencies, rheumatic diseases
Fully 48% of patients with autoimmune rheumatic diseases who developed persistent hypogammaglobulinemia after initiating treatment with...
From the Journals
Lower TNF inhibitor efficacy observed in women with nonradiographic axSpA
Findings are similar to those reported for sex differences in TNF inhibitor response seen in radiographic disease.
News from the FDA/CDC
FDA issues new NSAIDs warning for second half of pregnancy
The FDA action expands on earlier warnings about agents in this drug class, which the FDA previously cautioned about taking after week 30 of...
Feature
CDER chief reflects on advances in rare diseases
“People always call me fearless, but I feel like I just state the facts,” Dr. Janet Woodcock said.
From the Journals
Shingrix effective in older adults with preexisting immune-mediated disorders
The most common immune-mediated disorders in two phase 3 clinical trials of the vaccine were psoriasis, spondyloarthropathy, rheumatoid arthritis...
Conference Coverage
Strategic approach mitigates impact of antidrug antibodies in patients with rheumatic diseases
Consider dose escalation and adding an immunomodulator to overcome the impact of antidrug antibodies in rheumatic disease patients.
Conference Coverage
Dr. Len Calabrese gives advice on vaccinating adult patients with rheumatic disease
He highlights safety protocols and advises on recommended vaccines in rheumatology practice.
From the Journals
Trabecular bone loss may contribute to axial spondyloarthritis progression
Severe trabecular bone loss is associated with syndesmophyte formation in axial spondyloarthritis.
From the Journals
TNF inhibitors linked to inflammatory CNS events
The authors do not caution “against using these therapies in appropriate patients,” and it is unclear whether this association “represents de novo...
Latest News
Humira topped drug-revenue list for 2019
Three cytokine inhibitors were among the four best-selling drugs last year.
From the Journals
Obesity negatively affects axial spondyloarthritis disease activity
Obese patients with axial spondyloarthritis showed significantly greater disease activity than did normal weight patients.