STATISTICAL ANALYSIS
Data from all studies were pooled and descriptive statistics were reported as weighted mean ± weighted standard deviation for continuous variables and frequency with percentage for categorical variables. A meta-analysis was performed for all outcome measures that were reported in 3 or more studies within a specific treatment cohort. Data were analyzed using 2-sample and 2-proportion Z-tests. Results were considered statistically significant at P < .05.
RESULTS
LITERATURE RESEARCH
Using the aforementioned search strategy, 154 studies were identified. Following application of the inclusion and exclusion criteria, 35 studies were included in the analysis (Figure 1). One study compared open and percutaneous techniques, and another compared arthroscopic and percutaneous techniques, rendering a total of 19 studies examining open surgical techniques for treatment of lateral epicondylitis,3-21 12 studies examining arthroscopic techniques,14,22-32 and 6 studies reporting percutaneous surgical treatment of lateral epicondylitis29,33-37 (Table 2). There was1 level I study (3%), 6 level III studies (17%), and 28 level IV studies (80%).
Table 2. Study Demographic Data for Open, Arthroscopic, and Percutaneous Lateral Epicondylectomy
Open | Arthroscopic | Percutaneous | Total | |
Number of studies | 19 | 12 | 6 | 35 |
Level of evidence | ||||
I | 1 (5%) | 0 | 0 | 1 (3%) |
II | 0 | 0 | 0 | 0 |
III | 3 (16%) | 4 (33%) | 1 (17%) | 6 (17%) |
IV | 15 (79%) | 8 (67%) | 5 (83%) | 28 (80%) |
US: International | 8:12 | 3:9 | 1:5 | 12:24 |
Journals of publication | ||||
AJSM | 3 | 1 | 1 | 5 |
JSES | 2 | 2 | 1 | 5 |
Arthroscopy | 2 | 2 | 0 | 3 |
KSSTA | 1 | 2 | 0 | 3 |
CORR | 0 | 2 | 0 | 2 |
JHS | 0 | 1 | 0 | 1 |
JOS | 1 | 1 | 0 | 2 |
AJO | 2 | 0 | 0 | 2 |
Other | 8 | 1 | 4 | 12 |
Abbreviations: AJO, The American Journal of Orthopedics; AJSM, American Journal of Sports Medicine; Arthroscopy, The Journal of Arthroscopy and Related Surgery; CORR, Clinical Orthopaedics & Related Research; JHS, Journal of Hand Surgery; JOS, Journal of Orthopaedic Surgery; JSES, Journal of Shoulder and Elbow Surgery; KSSTA, Knee Surgery, Sports Traumatology, and Arthroscopy.
SUBJECT DEMOGRAPHICS
The 35 included studies comprised 1579 patients and 1640 elbows. Among these, 1055 (64%) elbows underwent open (O), 401 (25%) underwent arthroscopic (A), and 184 (11%) underwent percutaneous (P) treatment. The average age was 45.7 years, 47% of the patients were male, 43% were laborers, 31% had worker’s compensation claims, and the dominant extremity was involved in 62% of patients. The percutaneous cohort was older than the open cohort (P = 46.9, O = 45.4, A = 45.8; P = .036). The duration of symptoms was shorter in the percutaneous cohort than in the other 2 groups and shorter in the arthroscopic cohort than in the open cohort (P = 8 months, O = 23 months, A = 18 months; P < .001). There were no significant differences between groups regarding gender, occupation, worker’s compensation status, or involvement of the dominant extremity (Table 3).
Table 3. Subject Demographics for Open, Arthroscopic, and Percutaneous Groups
Open | Arthroscopic | Percutaneous | |
Subjects (N) | 999 | 397 | 183 |
Elbows (N) | 1055 | 401 | 184 |
Elbows with follow-up (%) | 915 (87%) | 350 (87%) | 181 (98%) |
Males (%) | 427 (47%) | 173 (49%) | 78 (43%) |
Females (%) | 488 (53%) | 177 (51%) | 103 (57%) |
Mean age (years) | 45.4 | 45.8 | 46.9 |
Dominant elbow (%) | 70% | 69% | 53% |
Laborer (%) | 56% | 53% | 48% |
Work comp (%) | 36% | 30% | NR |
Symptoms to operation (months) | 23 | 18 | 8 |
Min. symptoms to operation (months) | 6 | 6 | 3 |
Mean follow-up (months) | 60 | 44 | 11 |
MATA-ANALYSIS CLINICAL OUTCOMES
Clinical outcome results were pooled for all studies reporting the same outcome measure for the same technique (open, arthroscopic, or percutaneous). A meta-analysis was performed for all outcome measures that were reported in a minimum of 3 studies utilizing the same surgical technique (Table 4).
PAIN RELIEF
Thirteen open studies,3,5,7,8,11-16,18,19,21 7 arthroscopic studies14,22-24,26,27,31 and 0 percutaneous studies reported the proportion of patients who were pain free at final follow-up. The proportion of patients who were pain free following open débridement was greater than that in the arthroscopic cohort (O = 70%, A = 60%; P = .009) (Table 4).
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