Among the CPM patients, 40% of complications occurred on the CPM side.
In a multivariate analysis controlling for age, body mass index, diabetes, previous radiation, smoking history and reconstruction type, CPM was associated with an odds ratio for any complication of 1.5 (P = .029) and 2.6 for major complications (P = .007).
"We believe that patients considering CPM should be made aware of these risks, and certainly more research is needed on patient decision pathways and shared decision making," Dr. Miller said.
Both Dr. Carson’s and Dr. Miller’s studies were internally funded. Dr. Carson disclosed serving on the NCCN Board of Directors. Dr. Miller reported having no financial disclosures.