News
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Assess patient’s body clock before treating circadian rhythm sleep disorders
- Author:
- Amy Karon
Key clinical point: Clinicians should measure dim light melatonin onset before treating patients with circadian rhythm sleep disorders, and should...
News
Multiples of median OS predicted actual survival in metastatic colorectal cancer
- Author:
- Amy Karon
Key clinical point: Clinicians can use simple multiples of median overall survival times from clinical trials to estimate survival percentiles for...
News
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Recent Use of Oral Contraceptives Linked to Breast Cancer
- Author:
- Amy Karon
Key clinical point: Recent use of oral contraceptives may increase breast cancer risk.Major finding: Oral contraceptive use within the prior year...
News
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Life expectancy approached 40 years for children born with CF in 2010
- Author:
- Amy Karon
Key clinical point: Patients with cystic fibrosis who are born and diagnosed in 2010 can expect to live almost 40 years if clinical care remains...
News
MS disability linked to abnormalities of spinal cord grey matter
- Author:
- Amy Karon
Key clinical point: Pathology of spinal cord grey matter contributes to disability in MS, especially in patients with secondary-progressive MS....
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Older age at primary progressive MS onset predicted faster disability accumulation
- Author:
- Amy Karon
Key clinical point: Older age at disease onset predicted faster disability accumulation in patients with primary progressive multiple sclerosis....
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Study identified predictors of ICU survival in lung cancer patients
- Author:
- Amy Karon
Key clinical point: Palliative care may be a better option than ICU admission for lung cancer patients deemed unfit for anticancer treatment who...
News
Chikungunya Vaccine Safe, Immunogenic in Phase I Trial
- Author:
- Amy Karon
Key clinical point: A novel, noninfectious vaccine for chikungunya virus was highly immunogenic and caused no serious adverse effects in a phase I...
News
Chikungunya vaccine safe, immunogenic in phase I trial
- Author:
- Amy Karon
Key clinical point: A novel, noninfectious vaccine for chikungunya virus was highly immunogenic and caused no serious adverse effects in a phase I...
News
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Review finds sparse evidence for sleep/wake drugs in shift workers
- Author:
- Amy Karon
Key clinical point: Sparse evidence supports the use of sleep- and wakefulness-promoting drugs in shift workers, and both sleep- and wakefulness-...
News
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Diabetes, hypertension drive higher CVD risk in blacks and women
- Author:
- Amy Karon
Key clinical point: Cardiovascular risk factors disproportionately affect blacks and women; and while the gender gap has narrowed, the disparity...
News
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Twin study confirmed genetic basis of several epilepsy syndromes
- Author:
- Amy Karon
Key clinical point: A study of pairs of twins confirmed the genetic basis of specific epilepsies.Major finding: Twin concordance estimates for...
News
Guidelines, quality indicators found lacking for CVD in RA
- Author:
- Amy Karon
Key clinical point: Guidelines and quality indicators on preventing cardiovascular disease in patients with rheumatoid arthritis (RA) are sparse...
News
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One in six SLE patients readmitted in 30 days
- Author:
- Amy Karon
Key clinical point: One in six patients with systemic lupus erythematosus (SLE) was readmitted to the hospital within 30 days of discharge, and...
News
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PALB2 mutation increased lifetime risk of breast cancer
- Author:
- Amy Karon
Key clinical point: Inherited loss-of-function mutations in PALB2 significantly increase women’s lifetime risk of breast cancer.Major finding:...