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Radioimmunotherapy and gemcitabine showed promise in metastatic pancreatic ductal cancer
- Author:
- Amy Karon
Major finding: Median overall survival was 7.9 months with multiple cycles of gemcitabine plus 90Y-clivatuzumab tetraxetan, vs.
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Relative tumor size improved predictive value of PET scans in advanced-stage Hodgkin’s lymphoma
- Author:
- Amy Karon
Major finding: Patients with less than 40% tumor reduction after chemotherapy had a 23.1% risk of progression or relapse within the first year,...
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Basal cell cancer incidence higher than previously reported
- Author:
- Amy Karon
Major finding: The incidence of basal cell carcinoma in northern California rose by about 13% from 1998 through 2012.Data source: Registry of...
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Buccal acyclovir delays recurrence of herpes labialis
- Author:
- Amy Karon
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Nonmelanoma skin cancer linked to increased fracture risk in postmenopausal women
- Author:
- Amy Karon
Key clinical point: A history of nonmelanoma skin cancer may predispose patients to bone fractures.Major finding: Incident lower arm fracture was...
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NSAID use linked to reduced risk for second nonmelanoma skin cancer
- Author:
- Amy Karon
Key clinical point: NSAID use is associated with a lower risk of a second nonmelanoma skin cancer in white women.Major finding: In women with a...
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Using cyclosporine A: Study sheds light on inflammatory mechanisms in atopic dermatitis
- Author:
- Amy Karon
Key clinical point: Clinical improvements in atopic dermatitis correlated with reductions in inflammatory markers.Major finding: SCORAD scores...
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Topical tazarotene did not improve response to imiquimod 5% in lentigo maligna
- Author:
- Amy Karon
Key clinical point: Patients with higher levels of inflammation in response to topical therapy were more likely not to have residual tumor at...
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Infrared detector distinguished malignant and benign skin lesions
- Author:
- Amy Karon
Major finding: Malignant skin lesions (basal cell carcinomas, squamous cell carcinomas, and malignant melanomas) were distinguished from benign...
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Single-fraction radiation therapy showed promise in metastatic Merkel cell carcinoma
- Author:
- Amy Karon
Major finding: Complete response was seen in 52% of tumors in high-risk patients and 81% of tumors in low-risk patients (P = .008).
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Benzodiazepines linked to worsened COPD in older adults
- Author:
- Amy Karon
Major finding: Compared with nonusers, new users of benzodiazepines were significantly more likely to be prescribed oral corticosteroids or...
News
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Nocturnal cortisol levels predicted neurocognitive impairment in sleep apnea
- Author:
- Amy Karon
Major finding: Nighttime cortisol levels accounted for 9%-16% of variance in learning, memory, and working memory, and apnea severity did not...
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Mixed results for the anti-EGFR panitumumab in KRAS exon 2 colorectal cancer
- Author:
- Amy Karon
Major finding: The primary endpoint, progression-free survival, was similar between groups (HR, 0.87; 95% CI, 0.65-1.17; P = .353). Median overall...
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Lower-dose chest radiation in childhood still carries high risk for breast cancer
- Author:
- Amy Karon
Major finding: Whole-lung irradiation in childhood was associated with a high risk of subsequent breast cancer, compared with that in the general...
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Statin Users Eat More, Gain More Weight
- Author:
- Amy Karon