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Biologic may bring relief for children and adults with XLH syndrome
DENVER – Studies in adults and children with X-Linked hypophosphatemia show benefit with a monoclonal antibody that boosts serum levels of...
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ACP osteoporosis treatment guideline debated
DENVER – An endocrinologist and a primary care physician debate the merits of the American College of Physicians osteoporosis treatment guideline...
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In hypoparathyroidism, phosphate, calcium levels may matter
A case-control study showed higher risks of complications in hypoparathyroidism with phosphate and calcium-phosphate levels above the median.
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Romosozumab reduces fracture risk out to 36 months, with no signs of cardiovascular problems
Taking romosozumab followed by denosumab led to fewer fractures and greater bone density increases than did placebo followed by denosumab.
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Teriparatide reduces fractures over risedronate in all subgroups with osteoporosis
DENVER – “I don’t think it’s a question of if, but when to use an anabolic therapy,” Dr. Fahrleitner-Pammer said.
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Preferred osteoporosis treatment order with teriparatide, denosumab reaffirmed
DENVER – The findings reinforce the use of an anabolic agent followed by an antiresorptive agent, rather than the other way around.
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Immunologic testing is key to diagnosing autoimmune blistering diseases
SAN FRANCISCO – Starting with immunologic testing can spare patients with blistering diseases years of unnecessary overexposure to prednisone.
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Know the best specific signs for polycystic ovary syndrome
Hirsutism and acanthosis nigricans are “the best specific signs for PCOS.”
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Mitotic rate not tied to SLN biopsy results in thin melanomas
SAN FRANCISCO – A survey of melanoma cases showed no correlation between mitotic rate in thin tumors and positive sentinel lymph node biopsy.
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Incidental hip CT scans could serve as osteoporosis screen
DENVER – Bone mineral density and femoral strength calculated from CT scans that had been taken for another purpose performed better than did DXA...
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Bar soaps may be better than body washes for contact dermatitis patients
SAN FRANCISCO – Liquid soaps had far more preservative and surfactant allergens than bar soaps, in a study comparing ingredients in the two...
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Diagnosing high-risk keratinocyte carcinomas in the dermatology clinic
These cancers can present with perineural invasion and associated neurological symptoms, which may be mistaken for Bell’s palsy or stroke.
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Reduced fracture risk maintained in abaloparatide extension study
At least one new vertebral fracture occurred in 0.9% of the women in the abaloparatide-alendronate group and in 5.6% of the placebo-alendronate...
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Study finds low risk for jaw osteonecrosis with denosumab for postmenopausal osteoporosis
An analysis of a 7-year, open-label extension study of denosumab in women found a 0.05% overall rate of jaw osteonecrosis and a 0.7% rate...
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Allopurinol extension trial backs treat-to-target approach in gout
The results alleviate fears of adverse events from heightened doses, especially in patients with impaired kidney function.