News
Biomarkers predict efficacy of DKN-01 in endometrial cancer
- Author:
- Neil Osterweil
High levels of DKK1 expression and the presence of Wnt or PIK3CA activating mutations are associated with better outcomes.
News
Gynecologic cancer patients at risk of insurance loss, ‘catastrophic’ costs
- Author:
- Neil Osterweil
The Affordable Care Act did not spare many gynecologic cancer patients from financial hardship.
News
Frail status may be better than age for predicting ovarian cancer outcomes
- Author:
- Neil Osterweil
Older, fit patients may be better candidates for ovarian cancer surgery than younger, more frail patients, a...
News
Omidubicel improves on umbilical cord blood transplants
- Author:
- Neil Osterweil
“Transplantation with omidubicel, compared to standard cord blood transplantation, results in faster...
News
Rucaparib extends PFS in BRCA-mutated ovarian cancer, with an exception
- Author:
- Neil Osterweil
The PARP inhibitor was superior to chemotherapy, except in patients with BRCA reversion mutations.
News
GVHD prophylaxis: Similar outcomes with PTCy and ATG
- Author:
- Neil Osterweil
There were no significant differences between posttransplant cyclophosphamide and antithymocyte globulin in...
News
Close joint health monitoring essential with new hemophilia therapies
- Author:
- Neil Osterweil
Physical joint examinations and patient-reported outcomes only are not sufficient for detecting subclinical...
News
Joint pain in patients with hemophilia may be neuropathic
- Author:
- Neil Osterweil
Objective pain measures and self-reported ankle pain in patients with hemophilia did not correlate with MRI...
News
Type 3 von Willebrand a rare but serious bleeding disorder
- Author:
- Neil Osterweil
The disease does not respond to desmopressin, and requires von Willebrand factor concentrate with or without...
News
Bleeding disorder diagnoses delayed by years in girls and women
- Author:
- Neil Osterweil
Despite girls having abnormally heavy menstrual bleeding, their families and physicians may not recognize signs...
News
Maribavir seen as superior to other antivirals for CMV clearance post transplant
- Author:
- Neil Osterweil
The novel antiviral was associated with a twofold improvement in CMV viremia clearance at 8 weeks of therapy...
News
CAR-T in children branching out to solid tumors
- Author:
- Neil Osterweil
Chimeric antigen receptor T-cells are being explored for treatment of pediatric sarcomas, glioblastomas/gliomas...
News
Safety profiles of hemophilia agents vary widely
- Author:
- Neil Osterweil
Within-class comparisons can be misleading; each antihemophilia agent, old and new, needs to be evaluated...
News
Using engineered T cells reduced acute, chronic GVHD
- Author:
- Neil Osterweil
GVHD and relapse-free survival outcomes were better with regulatory T cells given prior to stem cell transplant...
News
Transplant-related mortality higher with CD34 selection
- Author:
- Neil Osterweil
The lower incidence of chronic GVHD with CD34 selection was offset by the higher mortality, compared with other...