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TKI choice key for fit/unfit patients with Ph+ALL
Ponatinib (Iclusig) is associated with high response rates in combination therapy, but toxicities may be too great for less fit patients.
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Fatal pediatric melanomas diverse in presentation
One-fourth of fatal pediatric melanomas arose in association with congenital melanocytic nevi.
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Coronavirus-associated aspergillosis increased 30-day mortality risk
Nearly one-third of patients on mechanical ventilation for COVID-19 had probable coronavirus-associated pulmonary aspergillosis.
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Ultrasound, cardiac CT valuable in COVID-19 assessment
An expert panel of the American College of Cardiology offers evidence-based guidance for evaluating cardiac complications of COVID-19 infections...
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Ready for PRIME time? Newly ID’d cells predict RA flares
Preinflammatory mesenchymal cells resembling synovial fibroblasts may be markers for flare or potential therapeutic targets.
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The wheels on the bus take lung cancer screening to rural areas
A commercial bus, modified to carry a mobile CT screening unit, has been reaching high-risk individuals in rural areas who may have otherwise been...
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USPSTF: Earlier lung cancer screening can double eligibility
New proposals to start screening at age 50 rather than 55, and after 20 rather than 30 pack-years of smoking, could benefit Black and female...
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Inhaled treprostinil improves walk distance in patients with ILD-associated pulmonary hypertension
Clinical worsening was reduced for patients with interstitial lung disease–associated pulmonary hypertension, compared with placebo.
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Sotatercept reversed vascular remodeling in patients with PAH
The investigational fusion protein sotatercept is thought to reduce pulmonary vascular resistance by reversing remodeling.