News
First NCCN guideline on hematopoietic cell transplantation focuses on GVHD
- Author:
- Neil Osterweil
Diagnosis and management of both acute and chronic graft-versus-host disease is at the core of the recommendations.
News
Trifluridine/tipiracil effective in metastatic gastric cancer after gastrectomy
- Author:
- Neil Osterweil
FTD/TPI was associated with significantly better overall survival and progression-free survival than placebo in patients who had undergone...
News
Fresh RBCs offer no benefit over older cells in pediatric ICU
- Author:
- Neil Osterweil
SAN ANTONIO – Exposure to fresh red cells may be associated with immune suppression because viable white cells may also be present in the product...
News
ART traces in donor samples show risk to blood supply
- Author:
- Neil Osterweil
Metabolites of drugs used in HIV infection prophylaxis were found in a small proportion of blood samples from HIV-negative donors.
News
Fibrinogen concentrate effective, safe for postop bleeding
- Author:
- Neil Osterweil
SAN ANTONIO – Favored more in Europe than North America, fibrinogen concentrate was noninferior to cryoprecipitate for control of bleeding after...
News
SPARTAN: Apalutamide delays second progression in nonmetastatic CRPC
- Author:
- Neil Osterweil
BARCELONA – The androgen receptor inhibitor also appeared to show an overall survival benefit, but it did not reach significance in an interim...
News
Atezolizumab plus chemo gives slight PFS edge in mUC
- Author:
- Neil Osterweil
BARCELONA – Adding the immune checkpoint inhibitor atezolizumab to platinum-based chemotherapy offered a modest PFS benefit over chemotherapy...
News
Ribociclib/fulvestrant boosts survival in advanced breast cancer
- Author:
- Neil Osterweil
BARCELONA – The median overall survival for patients who received the CDK4/6 inhibitor plus fulvestrant has not been reached in the MONALEESA-3...
News
PARP inhibitor prolongs PFS in mCRPC
- Author:
- Neil Osterweil
BARCELONA – The PROfound trial shows that targeted therapy can be effective against metastatic castration-resistant prostate cancer bearing DNA...
News
Immunotherapy duo extends survival in first line for advanced NSCLC
- Author:
- Neil Osterweil
BARCELONA – Nivolumab and low-dose ipilimumab improved survival of patients with untreated advanced non–small cell lung cancer regardless of PD-L1...
News
Osimertinib improves survival in advanced NSCLC
- Author:
- Neil Osterweil
BARCELONA – Osimertinib is the first TKI to show a survival advantage over another in advanced non–small cell lung cancer, FLAURA investigators...
News
Adjuvant radiotherapy no better than salvage post prostatectomy
- Author:
- Neil Osterweil
BARCELONA – Men who underwent prostatectomy fared just as well with observation and salvage radiotherapy as with adjuvant radiotherapy.
News
Worse PFS when radiation is withheld in early-stage Hodgkin lymphoma
- Author:
- Neil Osterweil
Patients negative for disease on PET scans after two chemotherapy cycles fared better with consolidation radiotherapy.
News
PBRM1 mutations not quite up to snuff as ccRCC biomarkers
- Author:
- Neil Osterweil
Truncating mutations in PBRM1 are moderately linked to response to immune checkpoint inhibitors in metastatic clear cell renal cell carcinoma.
News
Stem cells gene edited to be HIV resistant treat ALL, but not HIV
- Author:
- Neil Osterweil
A patient with acute lymphoblastic leukemia (ALL) and HIV had a complete ALL remission after a CCR5-depleted...