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‘Remarkable’ results with CAR T cells could make chemo obsolete
“It’s really remarkable that the results are so far in favor of the CAR T-cell therapy that I think it’s inevitable that this will become the...
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Liver cancer risk lingers even after HCV eradication
Not having a sustained viral response was associated with a more than sevenfold higher risk for liver cancer in a multicenter study.
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ASH meeting: Diversity, inclusion, immunotherapy, and COVID-19
“While there have been many advances in the treatment of acute myeloid leukemia ... addressing end-of-life issues is an often neglected area.”
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NAFLD, ALD prevalent among teens, young adults
It’s important to “mitigate modifiable risk factors to prevent disease development and disease progression to potentially advanced fibrosis and...
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In pill or food form, healthy fatty acids reduce liver fat
For patients with NAFLD who supplement their diets with polyunsaturated fatty acids, liver and metabolic parameters improve, results of a...
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Immunotherapies for children with r/r ALL face off
Outcomes were better with tisagenlecleucel vs. blinatumomab in an indirect comparison, but clinical indications should determine which agent to...
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Adding rituximab to belimumab offers no help for lupus
The combination of rituximab and belimumab was associated with a longer duration of response, but there was no benefit of belimumab alone for...
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Allopurinol proves noninferior to febuxostat for gout relief
A randomized, treat-to-target trial showed that the two urate-lowering therapies were comparably effective and safe at doses titrated to target,...
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When a JAK inhibitor fails for a patient with RA, what’s next?
Cycling to a second JAK inhibitor and switching to a biologic disease-modifying antirheumatic drug were equally effective at ameliorating...
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Genotype, need for transfusion predict death in VEXAS syndrome
Among patients with a methionine-to-valine substitution in the UBA1 gene, survival was significantly worse, compared with patients with two other...
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Rituximab improves systemic sclerosis skin, lung symptoms
Patients who took rituximab in the DESIRES trial had better skin scores and lung function at 6 months than did patients who received placebo.
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Vitamin D and omega-3 supplements reduce autoimmune disease risk
“People who are otherwise healthy and have a family history of autoimmune disease might also consider starting to take these supplements.”
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Skin checks reduce all-cause but not melanoma-specific deaths
Routine skin checks, a surrogate for skin-cancer screening, did not outperform patient self-examination at detecting lesions.
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Convenience, not outcomes may drive robot-assisted surgeries
The sale of robotically assisted surgical devices is expected to reach $14 billion by 2028. The technology is enticing to both surgeons and...
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A single text message links CRC patients to valuable resources
The Colorectal Cancer Provider Outreach Program, CRC POP, helps bridge the gap between a colorectal cancer diagnosis and the first treatment...