NEW YORK — Women with hypertension were twice as likely to have sexual dysfunction as were normotensive women in a study of 417 women.
The results also showed that women with controlled hypertension had a significantly lower prevalence of sexual dysfunction than did women whose hypertension failed to reach goal levels during treatment, Dr. Michael Doumas reported at the annual meeting of the American Society of Hypertension.
But a third finding was that women who were treated with antihypertensive drugs had a higher prevalence of sexual dysfunction than did untreated women. Dr. Doumas speculated that this was caused by the effects of certain antihypertensive drugs, such as diuretics and β-blockers. Treatment with other drug types, the angiotensin-receptor blockers and ACE inhibitors, appeared to reduce sexual dysfunction, said Dr. Doumas, a physician in the department of internal medicine at the Hospital of Alexandroupolis in Athens.
The study enrolled 216 women with hypertension and 201 normotensive women. Their average age was about 48, and all were sexually active. The women completed a 19-question form that has been validated as a way to evaluate sexual function. Of the women with hypertension, 42% had scores indicating sexual dysfunction, compared with 19% in the normotensives, a significant difference.
Sexual dysfunction increased significantly with the duration of hypertension. Among women who had been hypertensive for fewer than 3 years, 16% had a score indicating sexual dysfunction; the rate rose to 33% in women with hypertension for 3–6 years and 79% in women with hypertension for more than 6 years. Age also showed a significant interaction with prevalence. Among women aged 31–40 years, the prevalence of dysfunction was 21%; the rate rose to 38% in women aged 41–50 and to 57% in women older than 50.
The prevalence of sexual dysfunction was 48% among women treated for hypertension, compared with 33% in the untreated hypertensives, a significant difference.