All three patients received methylprednisolone from contaminated lots at medical facilities that were identified by the Centers for Disease Control and Prevention as recipients of contaminated lots.
These cases show that clinicians should consider an atypical pathogenesis when small-vessel infarctions expand locally or when new infarctions develop in the same vascular territory. They also demonstrate the angioinvasive nature of some fungal species such as Exserohilum, which can lead to progressive vascular occlusion, the investigators said.
No relevant financial conflicts of interest were reported.