Feature

Supportive oncodermatology: Cancer advances spawn new subspecialty


 

Build it, and they will come

The Stanford (Calif.) Cancer Center is a good example of what happens once a supportive oncodermatology service is up and running.

The program there was the brainchild of dermatologist Bernice Kwong, MD, who helped launch it in 2012 with 2 half-day outpatient clinics per week.

“Once people knew we were there seeing patients, we needed to expand it to 3 half days, and within 6 months, we knew we had to be” in the cancer center daily, she said. “The oncologists felt we were helping them keep their patients on treatment longer; they didn’t have to stop therapy to sort out a rash.”

Currently, the clinic sees about 15 to 20 patients a day, but “we have more need than that,” said Dr. Kwong, who is trying to recruit more dermatologists to help.

“The need is huge. There’s so much room for growth,” she noted, but first, “you need the oncologists to be on board.”

Dermatologist Adam Friedman, MD, director of supportive oncodermatology at the George Washington University Cancer Center, Washington, says his program is on the other end of the growth curve since it was only launched in the spring of 2017. Only about 80 patients have been treated so far, and there’s one dedicated clinic day a month, although he is on call for urgent cases, as is the case for many of the other dermatologists interviewed for this story.

Dr. Adam Friedman, director of translational research and dermatology residency program director at George Washington University, Washington, DC

Dr. Adam Friedman

“The struggle has been getting oncologists to remember to send us their patients,” Dr. Friedman said. It would be preferable to do referrals before treatment, too, he added, because “we are starting to see that if we pretreat these patients, we can limit or even prevent their rashes altogether.” The acne-like eruptions with EGFR inhibitors are a good example. “If you pretreat a week or two beforehand with doxycycline, a topical steroid, moisturizer, and sun protection, you can actually prevent them,” he noted.

Dr. Friedman expects business will pick up soon once word gets out, just like at Dana-Farber/Brigham and Women’s, Stanford, and elsewhere. “The places with the greatest need are going to have these services first, and then you’ll see them pop up elsewhere. I think we are going to see more,” he said.

The birth of supportive oncodermatology

Dermatologist Mario Lacouture, MD, director of the oncodermatology program at Memorial Sloan Kettering Cancer Center, New York, is considered by many oncodermatologists to be the father of the field.

He started the very first program in 2005 at Northwestern University, Chicago, followed by the program at Sloan Kettering a few years later. He has helped train many of the leaders in the field and coined the phrase “supportive oncodermatology” as the senior author in the field’s seminal paper, published in 2011 (J Am Acad Dermatol. 2011 Sep;65[3]:624-35). That article, in turn, inspired at least a few young dermatologists to make supportive oncodermatology their career choice. Dr. Lacouture speaks regularly at oncology and dermatology meetings to raise awareness about how dermatologists can improve cancer care.

Dr. Mario Lacouture is the director of the oncodermatology program at Memorial Sloan Kettering Cancer Center, New York.

Dr. Mario Lacouture

His own awareness started when he was a dermatology resident at the University of Chicago; a mentor took him on oncology calls to see cancer patients with skin problems. “In many cases, the anticancer drugs keeping these people alive were being stopped because of skin problems that we, as dermatologists, could have treated relatively easily. I realized that there had to be something we could do so these patients could stay on their drugs and also have a better quality of life,” he said.

Cancer survivors were also a concern. “Cancer treatment has improved so much that people are living longer, but the majority of survivors have either temporary or permanent cutaneous problems that would benefit from dermatologic care. However, the oncology community and patients are usually not aware that there are things we can do to help,” Dr. Lacouture said.

The message seems to have gotten out, however, among the hundreds of oncologists affiliated with Sloan Kettering. Dr. Lacouture needs a team of supportive oncodermatologists to meet the demand, with walk-in clinics every day and round-the-clock call.

He anticipates a day when visiting a supportive oncodermatologist will be routine, even before the start of cancer treatment, just as people visit a dentist before bone marrow transplants or radiation treatment to the head and neck. The idea would be to prevent cutaneous toxicity, something Dr. Lacouture and his team are already doing at Sloan Kettering. In time, supportive oncodermatology “is something that is going to be instituted early on” in treatment, he said.

“It’s important for dermatologists to reach out to their local oncologists; they will see there are many, many cancer patients and survivors who would benefit immensely from their care,” he said.

Dr. Lacouture is a consultant for Galderma, Janssen, and Johnson & Johnson. The other dermatologists interviewed for this story had no relevant industry disclosures. La Roche-Posay, a subsidiary of L’Oreal, is helping fund the supportive oncodermatology program at George Washington University. The company is interested in using cosmetics to camouflage cancer treatment skin lesions, Dr. Friedman said. Dr. Friedman is a member of the Dermatology News advisory board.

aotto@frontlinemedcom.com

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