Conclusion
Feverfew is best known as an effective herbal alternative for treating migraine headaches. New evidence is emerging that numerous other health benefits might be derived from this plant, and particularly its chief component parthenolide. The findings regarding anticarcinogenic and anti-inflammatory capacity are promising and may soon have dermatologic implications.
Formulations must be developed to account for the allergenic potential of parthenolide. Recent success has been observed with parthenolide-depleted feverfew. The ability to take a naturally occurring ingredient and improve it by removing an undesirable part of the chemical structure is the future of "natural" skin care, in my opinion. Will we be seeing more of the tweaked ingredients? I believe we will.