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Update on Management of Keloids

The etiology of keloids is uncertain, especially because there are no animal models to study. They occur most often in dark-skinned individuals. African Americans form keloids more often than Caucasians by a ratio ranging from 5:1 to 16:1.


 

A. Paul Kelly, MD

Keloids are scars, unique to humans, that grow beyond the boundaries of a cutaneous injury, inflammation, burn, or surgical incision. Although benign, keloids are often aesthetically malignant. The etiology of keloids is uncertain. However, we do know that they occur more often in African-American and Asian than Caucasian patients. There is no one therapeutic modality that either prevents the formation of keloids or treats active or inactive lesions. Consequently, there are many therapeutic options. In this review, an approach to medical and surgical management of keloids is provided, as well as a review of experimental therapeutic modalities.

*For a PDF of the full article, click on the link to the left of this introduction.

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