Ecthyma Gangrenosum Caused by Escherichia coli Bacteremia: A Case Report and Review of the Literature
This article has been peer reviewed and approved by Michael Fisher, MD, Professor of Medicine, Albert Einstein College of Medicine. Review date: October 2009.
Drs. Patel, Perez, Viera, Halem, and Berman report no conflict of interest. The authors report no discussion of off-label use. Dr. Fisher reports no conflict of interest. The staff of CCME of Albert Einstein College of Medicine and Cutis® have no conflicts of interest with commercial interest related directly or indirectly to this educational activity. Dr. Patel was Clinical Research Fellow, Department of Dermatology, University of Miami, Miller School of Medicine, Florida, and currently is an intern, Jamaica Hospital Medical Center, New York. Dr. Perez is an advisory liason, Dr. Viera is Senior Clinical Research Fellow, and Dr. Berman is Professor of Dermatology, all from the Department of Dermatology, University of Miami. Dr. Halem is Assistant Clinical Professor of Dermatology, Columbia University Medical Center, New York, New York.
Jitendrakumar K. Patel, MD; Oliver A. Perez, MD; Martha H. Viera, MD; Monica Halem, MD; Brian Berman, MD, PhD
Ecthyma gangrenosum (EG) is a serious and well-recognized cutaneous condition. Development of EG is most commonly associated with Pseudomonas aeruginosa septicemia. Other organisms, such as Escherichia, coli have been identified less often as the cause of EG. We describe a 50-year-old man previously diagnosed with acute myelogenous leukemia (AML) who developed an E coli–colonized EG lesion secondary to E coli bacteremia. This case represents the seventh of its kind in the literature and the first case in a patient with AML. In addition, a brief review of the etiopathology and management of EG is presented.