Woronoff Ring Associated With Adalimumab Therapy for Psoriasis

In 1926, Woronoff first described a hypopigmented ring surrounding psoriatic plaques during UV treatment. Since then, the Woronoff ring has been noted with the use of psoralen plus UVA therapy, corticosteroids, the Goeckerman treatment, coal tar, anthralin, fumaric acid esters, and methotrexate, as well as over the natural course of untreated psoriasis. However, there is limited research investigating this phenomenon and only 1-sentence descriptions are typical in dermatologic textbooks. We report a case of Woronoff ring in association with adalimumab. Its presentation with the use of any biologic agent is unique.