Key clinical point: A prognostic nomogram based on six novel factors accurately predicted outcomes in patients with unresectable HCC after HAIC.
Major finding : After a median of 35.4 months, 358 patients died; the C-index of a nomagram using C-reactive protein, albumin-bilirubin grade, alpha fetoprotein, extrahepatic metastasis, portal vein invasion, and tumor size was 0.710, significantly better than a nomogram using six conventional staging systems.
Study details: The data come from 463 adults with unresectable hepatocellular carcinoma who initially received hepatic arterial infusion chemotherapy (HAIC) between January 2016 and December 2018.
Disclosures: The study was supported by the National Natural Science Foundation of China, the Natural Science Foundation of Guangdong Province, Science and Technology Planning Project of Guangdong Province, Science and Technology Planning Project of Guangzhou, and Clinical Trials project 5010 of Sun Yat-sen University. The researchers had no financial conflicts to disclose.
Source: Mei J et al. Eur J Radiol. 2021 Aug 4. doi: 10.1016/j.ejrad.2021.109890.