Clinical Edge Journal Scan

Prostate cancer: Preoperative mpMRI PI-RAD score is linked to upstaging


 

Key clinical point: A higher preoperative multiparametric magnetic resonance imaging (mpMRI) Prostate Imaging Reporting and Data System (PIā€RADS) score is associated with upstaging on surgical pathology in patients with prostate cancer.

Major finding: PI-RADS score was greater than 3 in 87% of patients. Upstaging was reported in 47% of patients. PI-RADS was an independent risk predictor for upstaging (adjusted odds ratio, 2.034; P < .001).

Study details: A retrospective study of 294 patients with prostate cancer who underwent a prostate mpMRI and radical prostatectomy between 2016 and 2020.

Disclosures: No funding source was identified for this work. The authors declared no conflict of interests.

Source: Pockros B et al. Prostate. 2021 Dec 8. doi: 10.1002/pros.24280 .

Recommended Reading

Clinical Edge Journal Scan Commentary: Prostate Cancer December 2021
Federal Practitioner
Nivolumab-docetaxel shows response in mCRPC
Federal Practitioner
Treatment-related regret is common in localized prostate cancer
Federal Practitioner
Prostate cancer: Patient- and surgeon-level variation in postsurgery sexual function outcomes
Federal Practitioner
Prostate cancer: Grade group 2 is associated with higher treatment rate
Federal Practitioner
Prostate cancer screening: Statins do not modify mortality risk
Federal Practitioner
Prostate cancer: Positive targeted cores increase upgradation risk in active surveillance
Federal Practitioner
Low-grade prostate cancer: Secondary treatment rates slightly higher with delayed surgery
Federal Practitioner
Prostate cancer: Severe urinary incontinence after surgery is common
Federal Practitioner
Prostate cancer: ADT use tied to high risk for dementia
Federal Practitioner