Summaries of Must-Read Clinical Literature, Guidelines, and FDA Actions
Hepatitis C in Children and Adolescents
Clin Ther; ePub 2018 Aug 11; Espinosa, et al
Lack of implementation of policies for hepatitis C virus (HCV) screening and therapy on most affected populations, specifically infants, children, and adolescents, is responsible for continuance of this infection, a recent study found. A limited search was conducted of the relevant literature on 2 topics: 1) the impact of HCV on infants exposed by vertical transmission, and 2) the impact of HCV infection on infected children and adolescents. Among the findings:
- Young people, including women of childbearing age, infants, children, and adolescents, are being especially affected by HCV infection secondary to the intravenous drug use and opioid epidemic.
- Estimates of young populations are misleading because universal HCV screening had not been implemented.
Espinosa C, Jhaveri R, Barritt AS 4th. Unique challenges of hepatitis C in infants, children, and adolescents. [Published online ahead of print August 11, 2018]. Clin Ther. doi:10.1016/j.clinthera.2018.07.010.
This Week's Must Reads
Must Reads in Hepatitis
Glecaprevir/Pibrentasvir Efficacy & Safety Assessed, J Hepatol; ePub 2018 Nov 23; D’Ambrosio, et al
HCV Infection Among Children & Young Persons, J Hepatol; ePub 2018 Nov 26; Modin, et al
HCV Patients with Limited Access to Antiviral Therapy, Dig Liver Dis; ePub 2018 Nov 29; Lens, et al
Progression in the Elimination of HCV Infection, PLoS One; ePub 2018 Dec 4; Juanbeltz, et al
Increased HCV Screening in Veteran Populations, Jt Comm J Qual Patient Saf; ePub 2018 Sep 25; Wray, et al