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Protein predicts prostate cancer prognosis

Publish date:: February 9, 2021

Key clinical point: Greater expression of the RNA-binding protein SNRPA1 was associated with worse prognosis in prostate cancer.

Major finding: Expression of SNRPA1 (small nuclear ribonucleoprotein polypeptide A) was positively associated with Gleason score, a measure of disease severity in prostate cancer, and SNRPA1 increased with Gleason score increases from 6 to 10.

Study details: The data come from an analysis of a database that included the mRNA expression profiles of 1,472 RNA-binding proteins.

Disclosures: The study was supported by the National Natural Science Foundation of China. The researchers had no financial conflicts to disclose.

Citation:

Yuan P et al. Aging. 2021 Jan 15. doi: 10.18632/aging.202387.

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