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HIV/Hepatitis Coinfection, Low Muscle Mass Linked

AIDS; ePub 2016 Aug 3; Gowda, Brown, et al

Publish date:: August 24, 2016

HIV/viral hepatitis-coinfected persons have a higher likelihood of low muscle mass than those with viral hepatitis monoinfection, HIV monoinfection, or neither infection, a recent study found. To this end, HIV viremia is an important risk factor for low muscle mass among coinfected persons. Researchers conducted a cross-sectional study of participants (n=3,518) in the Multicenter AIDS Cohort Study and Women’s Interagency HIV Study with anthropometry performed after January 1, 2000. They found:

• Among total participants (164 HIV/viral hepatitis; 223 viral hepatitis alone; 1,070 HIV alone; 2,061 uninfected), HIV/viral hepatitis-coinfected persons had a 3.50-fold, 1.93-fold, and 2.65-fold higher odds of low muscle mass than viral hepatitis-monoinfected, HIV-monoinfected, and uninfected persons, respectively.

• Lack of HIV RNA suppression was the only factor associated with low muscle mass in coinfected persons.

Citation: Gowda C, Brown TT, Compher C, et al. Prevalence and predictors of low muscle mass in HIV/viral hepatitis coinfection. [Published online ahead of print August 3, 2016]. AIDS. doi:10.1097/QAD.0000000000001213.

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