Anemia
News
Studies support testing for iron deficiency in young women
A pair of studies suggest physicians should consider testing female adolescents for iron deficiency within a few years of starting menses. Women...
News
Vaccine granted orphan designation for MDS
The US Food and Drug Administration (FDA) has granted orphan drug designation to DSP-7888, an investigational cancer peptide vaccine, for the...
News
FDA approves new treatment for sickle cell disease
The US Food and Drug Administration (FDA) has granted approval for L-glutamine oral powder (Endari), the first treatment approved to treat sickle...
News
FDA approves first new drug for sickle cell in nearly 20 years
A second drug is approved for this rare, serious, and potentially fatal disorder.
Conference Coverage
Luspatercept appears safe, effective in β-thalassemia
MADRID—Results of a phase 2 study have shown that luspatercept can produce sustained increases in hemoglobin and reductions in transfusion burden...
News
FDA clears use of reagents to detect hematopoietic neoplasia
The US Food and Drug Administration (FDA) has allowed marketing of the ClearLLab Reagent Panel, a combination of conjugated antibody cocktails...
News
SCD therapy granted access to PRIME program
The European Medicines Agency (EMA) has granted GBT440 access to the agency’s PRIority MEdicines (PRIME) program. GBT440 is being developed by...
From the Journals
Plasma lipoprotein perturbations likely contribute to sickle cell vasculopathy
Patients with sickle cell disease had reduced levels of HDL3 and altered functionality of HDL2, which were associated with an increased...
Conference Coverage
T-cell product improves outcomes of haplo-HSCT
MADRID—Updated results of a phase 1/2 study suggest the T-cell product BPX-501 lowers the risks associated with haploidentical hematopoietic stem...
Conference Coverage
Gene editing aims to recreate beneficial mutation in SCD, beta-thalassemia
Production of fetal hemoglobin is protective against symptoms of these diseases.
News
Fostamatinib under review by FDA for chronic ITP
The US Food and Drug Administration (FDA) has accepted a new drug application (NDA) for the use of fostamatinib disodium (Tavalisse™) in the...