Clinical Edge Journal Scan

Risk of organizing pneumonia high in MDS patients with der(1;7)(q10; p10) abnormality


 

Key clinical point: There could be a possible relationship between organizing pneumonia (OP) and karyotype der(1;7)(q10; p10) in myelodysplastic syndrome (MDS).

Major finding: Overall, 5 (3.1%) patients developed pathologically diagnosed OP, of which 3 had der(1;7)(q10; p10) abnormality. The chances of developing OP was higher among patients with vs. without der(1;7)(q10;p10) abnormality (odds ratio, 25.70; 95% confidence interval, 2.582-347.400).

Study details : Findings are from a retrospective analysis of 159 patients with high-risk MDS.

Disclosures: No funding source was identified. The authors declared no potential conflicts of interest.

Source: Matsunawa M et al. Br J Haematol. 2021 Apr 14. doi: 10.1111/bjh.17473 .

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