Key clinical point: Compared with fecal immunochemical test (FIT), colonoscopy is a more effective method for improving survival among patients with colorectal cancer (CRC).
Major finding: Compared with no screening, colonoscopy led to a 44% decrease in mortality (adjusted hazard ratio [aHR] 0.56; 95% CI 0.53-0.59), whereas FIT reduced mortality by 22% (aHR 0.78; 95% CI 0.74-0.82).
Study details: This nationwide population-based retrospective study included 24,875 patients with CRC who underwent colonoscopy (n = 9619), FIT (n = 6936), or no screening (n = 8320).
Disclosures: This study was sponsored by the Catholic Medical Center Research Foundation, USA. The authors declared no conflicts of interest.
Source: Sung S-Y et al. Colonoscopy decreases mortality in colorectal cancer patients compared with fecal immunochemical test. J Gastroenterol Hepatol. 2022 (Jun 23). Doi: 10.1111/jgh.15924