Clinical Edge Journal Scan

Endoscopic resection could replace gastrectomy as the standard treatment for early gastric cancer


 

Key clinical point: Endoscopic resection (ER) achieves favorable long-term survival outcomes in patients with early gastric cancer (EGC) in the real-world setting.

Major finding: The overall 5-year overall survival (OS) rate was 89.0% (95% CI 88.3%-89.6%). The lower limit of the 95% CI for the 5-year OS rate exceeded the threshold 5-year OS rate in all categories of pathological curability, including curative resection for expanded indications.

Study details: The data come from a multicenter prospective cohort study, J-WEB/EGC, that included 9054 patients with 10,021 EGC lesions who underwent ER.

Disclosures: This study was supported by the Japanese Ministry of Health, Labour, and Welfare, and Daiwa Securities Health Foundation. The authors declared no conflicts of interest.

Source: Suzuki H et al. Long-term survival after endoscopic resection for gastric cancer: Real-world evidence from a multicenter prospective cohort. Clin Gastroenterol Hepatol. 2022 (Aug 7). Doi: 10.1016/j.cgh.2022.07.029

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