Key clinical point: In patients with early gastric cancer (EGC), pylorus-preserving gastrectomy (PPG) vs conventional distal gastrectomy (CDG) results in the harvest of fewer lymph nodes at stations 5, 6, 9, and 11p but similar survival outcomes.
Major finding: Patients who underwent PPG vs CDG had significantly lower numbers of lymph nodes harvested at stations 5, 6, 9, and 11p (weighted mean difference, −3.09; P < .001) but similar overall survival (hazard ratio [HR] 0.63; P = .852) and recurrence-free survival (HR 0.29; P = .900).
Study details: This was a meta-analysis of 16 studies including 4500 patients with EGC who had undergone PPG or CDG with lymph node dissection.
Disclosures: This study was sponsored by the Peking University People’s Hospital Research and Development Fund. The authors declared no conflicts of interest.
Source: Hou S et al. Pathological and oncological outcomes of pylorus-preserving versus conventional distal gastrectomy in early gastric cancer: A systematic review and meta-analysis. World J Surg Oncol. 2022;20:308 (Sep 24). Doi: 10.1186/s12957-022-02766-0