Primary prostate and colorectal carcinomas represent the most common primary cancers in men in the United States;1 however, rarely do the two cancers present within the same patient, and only anecdotal reports have identified synchronous presentation.2–6 Although a primary surgical approach has been described in most of those reports, 2–4 we here report the successful use of preoperative chemoradiotherapy followed by rectal tumor resection in the community setting for a patient with synchronous presentation of primary prostate and rectal carcinomas.
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