A 79-year-old woman with a history of non-small cell carcinoma of the right lung, stage IIB (T3, N0, M0) was treated with definitive chemoradiation, with 6,480 cGy given to the right upper lobe and mediastinum with concomitant chemotherapy. On a follow-up visit 3 months later, PET-CT imaging showed remarkable improvement in her tumor response, with evidence of tumor regression on CT. The patient was in her normal state of health until 4 months later, when she began complaining of headaches and her son noted that she was disoriented, confused, mildly aphasic, and unstable.
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