Bleeding Disorders
Feature
Sickle cell patients suffer discrimination, poor care – and shorter lives
Sickle cell disease is “a microcosm of how issues of race, ethnicity and identity come into conflict with issues of health care.”
News
Product can improve joint health in hemophilia A
New research suggests prophylaxis with a recombinant factor VIII Fc fusion protein (rFVIIIFc) can improve joint health over time in patients with...
News
Hemophilia B therapy approved in Saudi Arabia
The Saudi Food and Drug Authority has approved eftrenonacog alfa (Alprolix®) for the treatment of hemophilia B in the Kingdom of Saudi Arabia....
News
Gene therapy granted orphan designation for hemophilia A
The US Food and Drug Administration (FDA) has accepted an investigational new drug application for SHP654 (also known as BAX 888) and granted the...
News
Eltrombopag can control ITP long-term, study suggests
Eltrombopag can provide long-term disease control for chronic/persistent immune thrombocytopenia (ITP), according to research published in Blood...
News
Caplacizumab may enhance treatment of aTTP
Caplacizumab can improve upon standard care for patients with acquired thrombotic thrombocytopenic purpura (aTTP), according to results reported...
News
Japan approves product for hemophilia A
Japan’s Ministry of Health, Labor and Welfare has approved lonoctocog alfa (AFSTYLA®), a recombinant single-chain coagulation factor VIII product...
News
FDA grants factor IX therapy orphan designation
The US Food and Drug Administration (FDA) has granted orphan drug designation to CB 2679d/ISU304, a clinical stage drug candidate for hemophilia B...
Clinical Review
Disseminated Intravascular Coagulation
In the normal person, the process of coagulation is finely controlled at many levels to ensure the appropriate amount of hemostasis at the...
News
EMA issues final opinion on FVIII products
The European Medicines Agency (EMA) has concluded there is “no clear and consistent evidence” of a difference in inhibitor development between the...
From the Journals
Study advances noninvasive prenatal testing for hemophilia
Digital droplet PCR and targeted massively parallel sequencing (MPS) are accurate, noninvasive tests that can be used in pregnancy.