Bleeding Disorders
News
FDA grants drug orphan designation for PNH
The US Food and Drug Administration (FDA) has granted orphan drug designation to RA101495 for the treatment of paroxysmal nocturnal hemoglobinuria...
News
Product granted fast track designation for aTTP
The US Food and Drug Administration (FDA) has granted fast track designation to caplacizumab, an anti-von Willebrand factor (vWF) nanobody being...
From the Journals
Allele-matching in cord blood transplant yields better survival
Matching down to the allele level in umbilical cord blood transplantation between unrelated donors results in greater overall survival for those...
News
Vaccination does not eliminate risk for meningococcal disease in eculizumab recipients
CDC advises vigilance for meningococcal disease in all eculizumab users.
Conference Coverage
Monthly fitusiran showed promise in small phase I hemophilia trial
Monthly drug means good news for hemophilia A and B patients.
From the Journals
Prophylactic emicizumab cut bleeds by 87% in hemophilia A with inhibitors
The results of this phase III trial offer “an elegant new solution for treatment.”
News
Fostamatinib under review by FDA for chronic ITP
The US Food and Drug Administration (FDA) has accepted a new drug application (NDA) for the use of fostamatinib disodium (Tavalisse™) in the...
News
FDA approves Rebinyn for hemophilia B treatment
Rebinyn is intended to control and treat bleeding episodes, as well as provide perioperative management of bleeding.
News
FDA advisory committee supports L-glutamine for SCD
L-glutamine powder got the nod from the majority of the FDA’s Oncologic Drugs Advisory Committee for treatment of sickle cell disease.
Conference Coverage
Consider switch to clopidogrel for DAPT early post ACS
PARIS – TOPIC trial provides new evidence-based DAPT strategy.
Conference Coverage
Intensive BP lowering may reduce larger hematoma expansion in ICH
BOSTON – Intensive systolic blood pressure reduction did not significantly reduce hematoma expansion, except in those with larger hematomas.