Bleeding Disorders
Conference Coverage
ASH: Genes affecting risk, severity of chronic ITP are identified
Key clinical point: IFNA17 and IFNLR1 may be important candidate genes involved in immune regulation and sustained autoimmunity in immune...
Conference Coverage
Lusutrombopag is effective for thrombocytopenia in liver disease
Key clinical point: In a phase III trial, lusutrombopag was found to reduce the need for platelet transfusion in chronic liver disease patients...
News
FDA approves new treatment for Factor X deficiency
The Food and Drug Administration has provided its first approval of a coagulation factor replacement drug specifically for patients with...
News
FDA expands Promacta approval to include pediatric patients
News
Novel triple therapy in ITP provides enduring responses
A novel combination of dexamethasone, cyclosporine, and rituximab was well tolerated in patients with chronic ITP, and significantly increased...
News
Eltrombopag yields 40% response rate in pediatric immune thrombocytopenia
Key clinical point: Eltrombopag markedly outperformed placebo and had no new safety signals in children and adolescents with chronic immune...
News
Drug-induced iron deficiency decreased congenital erythropoietic porphyria symptoms
After 2 months of deferasirox therapy, the patient’s serum ferritin level dropped to 16 ng/mL
News
Dicloxacillin may cut INR levels in warfarin users
The antibiotic dicloxacillin appears to markedly decrease INR levels in patients taking warfarin.
News
World Federation of Hemophilia Seeks Proposals
Conference Coverage
Surgical bleeding risk ‘remarkable’ with platelet disorders
Key clinical point: Inherited platelet function disorders are associated with a significant surgical bleeding risk. Major finding: The frequency...
News
Gene therapy trial underway in hemophilia B
Key clinical point: BAX 335, a new gene therapy candidate, is now in a phase I-II trial in hemophilia B patients. Major finding: In the...