Bleeding Disorders
Guidelines
Study establishes protocol for perioperative dabigatran discontinuation
Key clinical point: The risk of stroke and major bleeding can be reduced to low levels using a formalized strategy for stopping and then...
Conference Coverage
Idarucizumab reverses dabigatran’s anticoagulant effects
Key clinical point: The investigational monoclonal antibody idarucizumab reversed the anticoagulant effects of dabigatran. Major finding:...
News
Promacta approved for pediatric treatment of chronic ITP
Conference Coverage
DDW: VIDEO: What we don’t know in the management of liver disease and coagulopathy
WASHINGTON – Your patient has cirrhosis, platelets 60,000 mm3, an INR of 2.0, serum creatinine of 1.2 mg/dL, and requires an endoscopic retrograde...
News
FDA approves new formulation of deferasirox for iron chelation
News
Lentiviral gene therapy could prove useful for adults with hemophilia
News
JAK inhibitor more effective than standard therapy for polycythemia vera
Key clinical point: Ruxolitinib, now approved for treatment of polycythemia vera in the United States, is an alternative to hydroxyurea in...
News
FDA expands ruxolitinib approval to include polycythemia vera
Clinical Review
Management of Bleeding Complications in Patients with Cancer
News
Drug gets orphan status for PNH in US
The US Food and Drug Administration (FDA) has granted the complement inhibitor AMY-101 orphan status as a treatment for paroxysmal nocturnal...
News
Drug granted orphan status for PNH in EU
A novel compound has received orphan status in the Europe Union to treat paroxysmal nocturnal hemoglobinuria (PNH), a life-threatening disease...