Bleeding Disorders
Conference Coverage
Fresh RBCs offer no benefit over older cells in pediatric ICU
SAN ANTONIO – Exposure to fresh red cells may be associated with immune suppression because viable white cells may also be present in the product...
From the Journals
Emicizumab effective in children with hemophilia A and inhibitors
Emicizumab stands to become the “next-generation standard of care” for these pediatric patients, report says.
Conference Coverage
Fibrinogen concentrate effective, safe for postop bleeding
SAN ANTONIO – Favored more in Europe than North America, fibrinogen concentrate was noninferior to cryoprecipitate for control of bleeding after...
From the Journals
Updated international consensus recommendations on management of acute upper GI bleeding
Updated guidelines on management of nonvariceal acute upper GI bleeding address questions on endoscopic techniques and pharmacologic management....
Guidelines
ISTH releases draft guideline for TTP diagnosis, treatment
The guideline provides recommendations for adult patients with either immune or hereditary TTP, from acute events through remission, including...
News
FDA gives nod to earlier use of Nplate in adults with ITP
The drug is now indicated for newly diagnosed and persistent adult patients with immune thrombocytopenia and an insufficient response to other...
From the Journals
Global blood supply runs low
Worldwide, more than 60% of countries had an inadequate supply of blood to meet the demand for transfusion.
Feature
Translucent particles found in Hemlibra
Genentech says the benefit-risk profile of the hemophilia A product is unchanged, and it will continue to be distributed.
From the Journals
Monthly and twice monthly emicizumab dosing safe for children with severe hemophilia A
The small study confirms the safety of twice-monthly or monthly emicizumab administration for children with severe hemophilia A without inhibitors...
From the Journals
New consensus recommendations on bleeding in acquired hemophilia
The key areas addressed in the global expert consensus statement include the initial management of bleeding and management of location-specific...
From the Journals
Hemophilia prevalence is nearly three times higher than previously reported
Dr. J. Michael Soucie of the Centers for Disease Control and Prevention said having more accurate prevalence data will help improve access to care...