Leukemia, Myelodysplasia, Transplantation
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Protein inhibition confers radioprotective effects
Researchers believe they may have discovered a method for treating and preventing radiation-induced gastrointestinal toxicity. The investigators...
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Monoclonal antibody could improve treatment of ALL
Credit: Linda Bartlett Preclinical research suggests the B-cell activating receptor (BAFF-R) may be a promising therapeutic target for treatment-...
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Team says antioxidant has no effect on cancer risk, overall health
Contrary to previous findings, a new study suggests the antioxidant resveratrol is not associated with improvements in health, including reducing...
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MRD test can predict HSCT outcomes in ALL patients
Credit: Graham Colm A method of measuring minimal residual disease (MRD) can predict transplant outcomes in adults with acute lymphoblastic...
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Method can track circulating cancer cells
Investigators have developed a technique that allowed them to track single tumor circulating in the blood of mice. The method, described in...
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Letermovir prevents CMV after hematopoietic-cell transplant
Major finding: At the conclusion of treatment, the rate of virologic failure was "markedly" lower in the 240-mg group (6%) than in the 120-mg...
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Protein interaction may be therapeutic target for AML
University of Queensland Inhibiting the interaction of 2 proteins can prevent the development of acute myeloid leukemia (AML), according to a...
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FDA approves CML drug for home administration
The US Food and Drug Administration (FDA) has expanded the approval of omacetaxine mepesuccinate (Synribo) to include home administration. The...
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Using chromatin conformation data to classify leukemia
Chromatin conformation can guide the classification of leukemia, according to research published in Genome Biology. Investigators mapped the...
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Stats show increase in cancer survival rates
Credit: NIH New statistics suggest 10-year survival rates for cancer patients in England and Wales have more than doubled over a 40-year period...
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Protein is key to HSC recovery after chemo, radiation
in the bone marrow The protein beta-catenin plays a critical role in promoting the recovery of hematopoietic stem cells (HSCs) after exposure to...