Leukemia, Myelodysplasia, Transplantation
Conference Coverage
Dual kinase inhibitor targets heterogeneity in AML
The inhibitor, SEL24-B489, targets both PIM and FLT3 mutants.
News
ASCO releases guidelines for managing cancer survivors
with a cancer patient NCI/Mathews Media Group The American Society of Clinical Oncology (ASCO) has issued 3 practice guidelines for preventing...
News
New indices risk-stratify adults with cytogenetically normal acute myeloid leukemia
Major Finding: Patients with index-defined low-, intermediate-, and high-risk disease had respective 5-year overall survival rates of 74%, 28%,...
News
Minimal residual disease associated with overall survival in leukemia
Major finding: MRD-negative status was independently associated with significantly longer progression-free survival and overall survival (P = 0.03...
News
Predicting risk of death in childhood cancer survivors
Logan Tuttle Factors other than cancer treatment or chronic health conditions can influence the risk of death among survivors of childhood...
Conference Coverage
Molecule can increase Hb in anemic cancer patients
The molecule, lexaptepid pegol (NOX-H94), is a pegylated L-stereoisomer RNA aptamer that binds and neutralizes hepcidin. In this phase 2 study, 5...
News
‘Extremely exciting’ results from phase I trial of novel cancer metabolism agent
Major finding: Among seven patients evaluable for efficacy, five achieved complete remission or complete remission with partial platelet count...
News
How NK cells kill abnormal blood cells
Credit: Bjorn Onfelt/Dan Davis New research provides additional insight into how natural killer (NK) cells eliminate abnormal hematopoietic cells...
News
Compound is potent FLT3 inhibitor, team says
Credit: Rhoda Baer An experimental compound called TTT-3002 could be “one of the most potent FLT3 inhibitors to date,” according to researchers...
Conference Coverage
Enrollment stalled for CAR T-cell study
Memorial Sloan-Kettering Cancer Center has temporarily suspended enrollment in a study of chimeric antigen receptor (CAR) T-cell therapy, due to 2...
Conference Coverage
How autophagy helps cancer cells evade death
Credit: Sarah Pfau SAN DIEGO—New research suggests that autophagy may allow cancer cells to recover and divide, rather than die, when faced with...