Melanoma
From the Journals
World Trade Center responders face greater cancer burden, including greater risk of multiple myeloma
The prevalence of multiple myeloma precursor disease was more than threefold higher in WTC exposed firefighters.
Conference Coverage
Early results favorable for combo TLR9 agonist + pembro in advanced melanoma
CHICAGO – The combination of pembrolizumab with CMP-001 is being evaluated as a strategy to overcome resistance to PD-1 blockade for patients with...
Conference Coverage
KEYNOTE-054: Adjuvant pembrolizumab beat placebo in high-risk resected melanoma
CHICAGO – One-year rates of recurrence-free survival for adjuvant pembrolizumab and placebo were 75% and 61%, respectively, in a phase 3 trial of...
Conference Coverage
Gene strong predictor of metastasis in melanoma
CHICAGO – Investigators have identified four genes that are overexpressed in primary melanoma, including one, CXCL1, that holds promise as a...
Conference Coverage
Extracapsular spread predicts survival in SLN+ melanoma
CHICAGO – Extracapsular spread may be an important indicator of PFS and OS in sentinel node positive micrometastatic melanoma.
Conference Coverage
What’s new in the latest melanoma guidelines
KAUAI, HAWAII – Eighth edition of AJCC staging manual brings better prognosis for many with stage III melanoma.
Conference Coverage
Surgery after immunotherapy effective in advanced melanoma
CHICAGO – Five-year survival was 75% in selected patients with advanced melanoma who had resection to no evidence of disease after immunotherapy...
Conference Coverage
Diabetes from checkpoint inhibitors probably means lifelong insulin
CHICAGO – In the largest case series to date, almost all patients remained on insulin at a median follow-up of 44 weeks, even after stopping ICIs...
From the Journals
Unknown primary melanoma looks a lot like known
Patients with metastatic melanoma of unknown primary had similar prognostic indicators to patients with known primary, but a small survival...
From the Journals
Melanoma in young children may be biologically distinct from that in teens
Children present with what appear to be more severe melanomas, but they are less likely to die than adolescents with melanomas.
Conference Coverage
U.S. adolescent malignant melanoma nearly halved during 2000-2014
SAN DIEGO – Adolescent malignant melanoma rate fell almost 50% from 2000 to 2014, contrasting with rising adult rates.