Melanoma
Conference Coverage
Novel immunostimulant combo shows early efficacy
SAN FRANCISCO – A one-two approach to stimulating both innate and adaptive immunity appears to be paying off, suggest early efficacy data from a...
Conference Coverage
Antibiotics gut checkpoint inhibitor efficacy
SAN FRANCISCO – Patients who had received antibiotics more than a month before a checkpoint inhibitor had significantly worse survival, regardless...
Conference Coverage
31-GEP test predicts likelihood of metastasis for cutaneous melanoma
WASHINGTON – “By using this one test, it’s able to separate out melanomas that otherwise may be grouped in together under current AJCC staging.”...
Conference Coverage
Diet appears to play an important role in response to anti-PD-1 cancer immunotherapy
Diet appears to affect response to anti-PD-1 cancer immunotherapy, likely by its effect on the gut microbiome.
News
FDA approves pembrolizumab for completely resected melanoma
Approval was based on improved recurrence-free survival in a randomized, double-blind, placebo-controlled, trial of 1,019 patients with completely...
From the Journals
Checkpoint inhibitors ‘viable treatment option’ in HIV-infected individuals
There were no concerning immune-mediated toxicities or changes in HIV-related parameters observed among 73 patients with HIV infection who had...
Conference Coverage
Immunotherapy’s cardiac effects require early monitoring, management
Immune checkpoint inhibitors and chimeric antigen receptor T cells can be highly effective against cancer, but can also harm the heart and...
Conference Coverage
The personal cancer vaccine NEO-PV-01 shows promise in metastatic cancers
WASHINGTON – The NEO-PV-1 neoantigen vaccine plus poly-ICLC adjuvant and nivolumab is well tolerated and shows clinical activity in metastatic...
From the Journals
Poor-prognosis cancers linked to highest suicide risk in first year
Pancreatic and lung cancer patients had high rates of suicide in comparison to the general population, while breast and prostate cancer patients...
Latest News
Pembrolizumab approved for Merkel cell carcinoma
The FDA granted accelerated approval for the drug based on promising results in nonrandomized, open-label trial.
From the Journals
More data link severe sleep apnea and aggressive melanoma
The findings offer further evidence of the link between cancer and sleep-disordered breathing.