Multiple Myeloma
News
Discovery could lead to better proteasome inhibitors
showing multiple myeloma A newly discovered mechanism has paved the way for the next generation of proteasome inhibitors, according to a paper...
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Drug shows early promise for hematologic malignancies
The drug, CPI-613, prompted responses in only 4 of 21 evaluable patients. However, 2 of those responses lasted more than 2 years. CPI-613 was...
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Cancer centers may not allow for dignified deaths
Credit: NCI and Mathews Media Group A new study suggests many patients in cancer centers do not experience a dignified death. Study...
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Regimen confers PFS benefit in newly diagnosed MM
Credit: CDC In the phase 3 FIRST trial, a regimen of continuous lenalidomide and low-dose dexamethasone conferred the greatest progression-free...
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Studies advance understanding of plasma cells
Murine studies have revealed signaling molecules that appear to play crucial roles in plasma cell development and survival. Investigators found...
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Group exploits autophagy to fight myeloma
Credit: Sarah Pfau Researchers have devised a strategy that leverages autophagy to work against multiple myeloma (MM). Their method involves...
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Program improves depression treatment in cancer
Credit: NIH Results of a large study suggest major depression is common—but largely untreated—among cancer patients in Scotland. And 2...
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Nanoparticle may have multiple cancer applications
Credit: PNAS A new type of nanoparticle (NP) could aid the diagnosis and treatment of cancers, according to research published in Nature...
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MM drug disappoints in phase 3 trial
Single-agent carfilzomib did not improve overall survival compared to an active control regimen of corticosteroids plus optional cyclophosphamide...
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Technique may predict progression in MM
Credit: Graham Colm Scientists have found that a technique used in Earth science research may be able to help physicians predict the course of...
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Enzyme plays key role in MM, group finds
Credit: Darren Baker Researchers have identified an enzyme that appears key to prognosis and progression in multiple myeloma (MM). The group...