Rare Diseases
Conference Coverage
Baseline imaging recommended in all Merkel cell carcinoma patients
CHICAGO – New data emphasize the need for routine baseline scans in patients with Merkel cell carcinoma.
Conference Coverage
Researchers propose new risk groups for NK-AML
NEWPORT BEACH, CALIF. – Investigators used machine learning algorithms to risk stratify patients with normal karyotype acute myeloid leukemia.
News
FDA approves ivosidenib frontline for certain AML patients
The expanded approval means that ivosidenib can be used first-line for acute myeloid leukemia patients with an IDH1 mutation who are not eligible...
From the Journals
Idelalisib shows long-term safety, efficacy for relapsed CLL
The long-term data confirm that the addition of idelalisib to rituximab significantly improves outcomes for patients with relapsed CLL. However,...
Conference Coverage
TTP death linked to elevated troponin and neurological signs
GLASGOW – The registry-based study showed that more than 70% of patients who presented with thrombotic thrombocytopenic purpura had neurological...
From the Journals
Tagraxofusp produces high response rate in BPDCN
The overall response rate was 90% in previously untreated patients who received the highest dose.
Conference Coverage
High-dose MTX-based chemo is well tolerated in older PCNSL patients
GLASGOW – A retrospective, real-world study suggests that older, fit patients can tolerate an intensive treatment regiment for primary central...
Conference Coverage
Creating CAR T-cell therapies for T-cell malignancies
NEWPORT BEACH, CALIF. – Dr. John F. DiPersio discusses preclinical research testing CAR T-cell therapies in T-cell malignancies.
Conference Coverage
Tumor-treating fields boost chemo for mesothelioma
GENEVA - Patients with malignant pleural mesothelioma who were treated with TTFields in combination with pemetrexed and...
From the Journals
Bendamustine/rituximab combo proves viable for comorbid CLL
Combination bendamustine and rituximab offers an effective treatment option for older, sicker patients with chronic lymphocytic leukemia.
Conference Coverage
Genetic variant increases stroke risk in childhood cancer survivors
ATLANTA - Dr. Yadav Sapkota of St. Jude Children's Research Hospital discusses the identification of a genetic variant that is strongly associated...