Rare Diseases
Conference Coverage
CAR T cells target HER2 expression in advanced sarcomas
ATLANTA – Although HER2 expression in osteosarcoma and rhabomyosarcoma is too low for HER2-targeted therapies such...
From the Journals
Case report may link gluteal implants to lymphoma
On the heels of increased reports of breast implant–related anaplastic large cell lymphoma, researchers report a case of lymphoma that may be...
Conference Coverage
Lentiviral gene therapy appears effective in X-CGD
HOUSTON – Results from the small study provide a “proof of concept” for the use of gene therapy in X-linked chronic granulomatous disease,...
From the Journals
Similar results for once- or twice-weekly carfilzomib in MM
There was no significant difference in safety or survival outcomes among patients with newly diagnosed multiple myeloma.
From the Journals
Trial supports less aggressive myeloma treatment
A less intensive transplant and maintenance strategy proved equally effective as more aggressive approaches in patients with multiple myeloma.
News
FDA approves caplacizumab for aTTP
The injection is approved in combination with plasma exchange and immunosuppressive therapy for adults with acquired thrombotic thrombocytopenia...
From the Journals
Meta-analysis: IVIG bests anti-D on platelet count in pediatric ITP
But the clinical significance of this finding is unclear because of the lack of data on bleeding symptoms, according to authors of the meta-...
From the Journals
Top cancer advance: Treatment of rare diseases
ASCO’s annual progress report names treatment of rare tumors as the Advance of the Year
From the Journals
Obinutuzumab-based regimens yield durable remissions in CLL
The findings suggest these new combinations may be more effective at clearing residual disease than rituximab-based therapy.
Daily News Podcast
Aspirin and Omega-3 fatty acids fail
Flu activity is ‘high’ in nine states.
Conference Coverage
ALL chemotherapy looks effective in mixed phenotype leukemia
SAN DIEGO – In a retrospective cohort study, most children with mixed phenotype acute leukemia achieved MRD-negative complete response on ALL-...