In his own study, Dr. Pandya and his associates compared a glycolic acid peel and hydroquinone to hydroquinone treatment alone in a split-face study of 21 women (Arch. Dermatol. 2002;138:1578-82). "The peel did not make a difference versus the side of face treated with hydroquinone only," Dr. Pandya said.
Although there are no published studies supporting or not supporting microdermabrasion in melasma, caution is advised when this approach is used, Dr. Pandya said. "If you are too aggressive, you can induce hyperpigmentation."
One of the biggest challenges for dermatologists may be convincing patients of the importance of using sunscreen for UV protection, not only while outside but if they remain indoors as well. "Visible light can also induce melanocyte formation, not just UVA or UVB," Dr. Pandya said. "That's bad news, because how many companies at this convention center will have a product that says 'This blocks visible light?’ The only thing we have is the thick stuff lifeguards put on their noses."
Dr. Pandya said, "Frequent application of broad spectrum and physical sunscreens, as well as avoidance of UV and visible light, are critical for long-term success."
Dr. Pandya said that he is a consultant for Galderma.