Key clinical point: Prevalence of migraine was higher in patients with celiac disease (CD) vs. healthy controls, with patients with CD and migraine showing worse gastrointestinal symptoms compared with those without migraine.
Major finding: The prevalence of migraine was higher in patients with vs. without CD (20.7% vs. 11.9%; P < .001). Patients with CD with vs. without migraine headache had a higher prevalence of abdominal pain (80.1% vs. 71.8%; P = .025), constipation (47.8% vs. 35.5%; P = .011), and diarrhea (60.8% vs. 45.9%; P = .002).
Study details: This case-control cross-sectional study included 1,000 adult patients with CD and 1,000 healthy controls.
Disclosures: No funding was received for this study. The authors declared no conflict of interests.
Source: Fanaeian MM et al. PLoS One. 2021;16(11):e0259502 (Nov 17). Doi: 10.1371/journal.pone.0259502.